Cancer Growth Is Orchestrated at the Cell Level, Not By a Central Process

“How are human tissues put together from single cells? The description above might suggest the involvement of master builders who oversee crews of workers, directing them in the detailed construction of normal and malignant tissues. In reality, there are no overseers forcing throngs of cells to line up and assemble themselves into normal or cancerous tissues. Architectural complexity in living tissue comes from the bricks themselves, the individual cells. Control is exercised from the bottom up…The cells forming a tumor are all lineal descendants of a single progenitor, a distant ancestor that lived many years before the tumor mass became apparent.” (p. 1-2)

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